bs-21990R

DATASHEET

Host: Rabbit

Target Protein: Complement C3d fragment

Immunogen Range: 991-1090/1663

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: P01024

Swiss Prot: 718

Source: KLH conjugated synthetic peptide derived from human Complement C3d fragment

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

The complement factor C3 consists of an alpha and a beta chain. C3 is a central factor in the complement cascade. It is central to the alternative pathway that leads to the C3 convertase C3bBb. The classical mannose binding lectin activation pathway leads to the C3 convertase C4b2a. These convertases cleave C3 resulting in C3a and C3b. Further degradation leads to the formation of the alpha chain products C3d, C3g and C3c. C3 is an acute phase protein that is produced by a wide range of tissues, including renal epithelial cells and hepatocytes.

Size: 100uL

Concentration: 1ug/ul

Applications: WB(1:300-5000)

Cross Reactive Species: Mouse

Predicted Cross Reactive Species: Human
Rat
Sheep
Pig

For research use only. Not intended for diagnostic or therapeutic use.