bs-2242R [Primary Antibody]
BMP7 Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: BMP7

Immunogen Range: 293-350/431


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 655

Swiss Prot: P18075

Source: KLH conjugated synthetic peptide derived from human BMP7

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
IHC-P(1:200-400)
IHC-F(1:100-500)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 15.7/47


Cross Reactive Species: Mouse
Rat
Dog
Rabbit

Predicted Cross Reactive Species: Human
Cow
Sheep
Pig
Horse
Chicken

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Mai et al. Dyssynchronous pacing triggers endothelial-mesenchymal transition through heterogeneity of mechanical stretch in a canine model. (2014) Circ.. 79:201-9Read more>>
  • Wang Y et al. SPARCL1 promotes C2C12 cell differentiation via BMP7-mediated BMP/TGF-β cell signaling pathway. Cell Death Dis. 2019 Nov 7;10(11):852.Read more>>
  • Shuxin Liu. et al. Overexpression of bone morphogenetic protein 7 reduces oligodendrocytes loss and promotes functional recovery after spinal cord injury. 2021 Aug 13Read more>>
  • Gulistan Sanem Saribas. et al. Ellagic acid increases implantation rates with its antifibrotic effect in the rat model of intrauterine adhesion. PATHOL RES PRACT. 2023 Jun;246:154499Read more>>
VALIDATION IMAGES

Formalin-fixed and paraffin embedded rabbit alveolar bone labeled with Anti-BMP7 Polyclonal Antibody, Unconjugated (bs-2242R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.


Formalin-fixed and paraffin embedded rabbit alveolar bone tissue labeled with Anti-BMP7 Polyclonal Antibody, Unconjugated (bs-2242R) at 1:300 followed by conjugation to the secondary antibody


Mouse bone lysates probed with BMP7 Polyclonal Antibody, Unconjugated (bs-2242R) at 1:300 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:10000 for 60 min at 37˚C.


Lane 1: Mouse Kidney lysates; Lane 2: Mouse Placenta lysates; Lane 3: Mouse Cerebrum lysates; Lane 4: Mouse NIH/3T3 cell lysates; Lane 5: Rat Cerebrum lysates probed with BMP7 Polyclonal Antibody, Unconjugated (bs-2242R) at 1:1000 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.