bs-23073R-BF680 [Conjugated Primary Antibody]
HES1 Polyclonal Antibody, AbBy Fluor-680 Conjugated
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Host: Rabbit

Target Protein: HES1

Immunogen Range: 251-280/280


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 3280

Swiss Prot: Q14469

Source: KLH conjugated synthetic peptide derived from human HES1

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity.

Conjugation: AbBy Fluor-680

Excitation/ Emission: 679nm/702nm

Size: 100µL

Concentration: 1ug/ul

Applications: IHC-P(1:200-400)
IHC-F(1:100-500)
IF(ICC)(1:50-200)
IF(1:50-200)

Predicted Molecular Weight: 30 kDa


Cross Reactive Species: Human

Predicted Cross Reactive Species: Mouse
Rat
Cow
Sheep
Pig
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Qu Ruyi. et al. RBPJ Knockdown Promotes M2 Macrophage Polarization Through Mitochondrial ROS-mediated Notch1-Jagged1-Hes1 Signaling Pathway in Uveitis. INFLAMMATION. 2024 May;:1-18Read more>>
  • Xiao-yue Guan. et al. Blocking Gremlin1 inhibits M1 macrophage polarization through Notch1/Hes1 signaling pathway in apical periodontitis. IMMUNOPHARM IMMUNOT. 2024 27Read more>>
VALIDATION IMAGES