bs-2367R [Primary Antibody]
ganglioside GM1 Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: ganglioside GM1

Clonality: Polyclonal

Isotype: IgG

Source: KLH conjugated ganglioside GM1 purified from bovine

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

A member of the family of glycosphingolipids, monosialoanglioside acts as a receptor and antigen for cholera. GM1 ganglioside, one of the glycosphingolipids widely distributed in all tissues, occurs in highest concentrations in the central nervous system (CNS). It is primarily located in the outer surface of the mammalian cell's plasma membrane and in synaptic membranes of the CNS. GM1 ganglioside modulates a number of cell surface and receptor activities as well as neuronal differentiation and development, protein phosphorilation and synaptic function.

Size: 100ul

Concentration: 1ug/ul

Applications: IHC-P()
IHC-F(1:100-500)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 1.57


Cross Reactive Species: Human
Rat
(Most Species )

Predicted Cross Reactive Species: Mouse
Dog
Cow
Pig
Horse
Rabbit
Guinea Pig

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Melani Solomon. et al. Altered blood-brain barrier transport of nanotherapeutics in lysosomal storage diseases. J CONTROL RELEASE. 2022 Sep;349:1031Read more>>
VALIDATION IMAGES

Formalin-fixed and paraffin-embedded human glioma tissue labeled with ganglioside GM1 Polyclonal Antibody, Unconjugated (bs-2367R) at 1:200 followed by conjugated secondary antibody and DAB staining


Formalin-fixed and paraffin-embedded rat brain tissue labeled with ganglioside GM1 Polyclonal Antibody, Unconjugated (bs-2367R) at 1:200 followed by conjugated secondary antibody and DAB staining


Formalin-fixed and paraffin-embedded rat brain tissue labeled with ganglioside GM1 Polyclonal Antibody, Unconjugated (bs-2367R) at 1:200 followed by conjugated secondary antibody and DAB staining.