DATASHEET
Host:
Rabbit
Target Protein:
ganglioside GM1
Clonality:
Polyclonal
Isotype:
IgG
Source:
KLH conjugated ganglioside GM1 purified from bovine
Purification:
Purified by Protein A.
Storage Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Background:
A member of the family of glycosphingolipids, monosialoanglioside acts as a receptor and antigen for cholera. GM1 ganglioside, one of the glycosphingolipids widely distributed in all tissues, occurs in highest concentrations in the central nervous system (CNS). It is primarily located in the outer surface of the mammalian cell's plasma membrane and in synaptic membranes of the CNS. GM1 ganglioside modulates a number of cell surface and receptor activities as well as neuronal differentiation and development, protein phosphorilation and synaptic function.
PRODUCT SPECIFIC PUBLICATIONS
- Melani Solomon. et al. Altered blood-brain barrier transport of nanotherapeutics in lysosomal storage diseases. J CONTROL RELEASE. 2022 Sep;349:1031Read more>>
VALIDATION IMAGES
Formalin-fixed and paraffin-embedded human glioma tissue labeled with ganglioside GM1 Polyclonal Antibody, Unconjugated (bs-2367R) at 1:200 followed by conjugated secondary antibody and DAB staining
Formalin-fixed and paraffin-embedded rat brain tissue labeled with ganglioside GM1 Polyclonal Antibody, Unconjugated (bs-2367R) at 1:200 followed by conjugated secondary antibody and DAB staining
Formalin-fixed and paraffin-embedded rat brain tissue labeled with ganglioside GM1 Polyclonal Antibody, Unconjugated (bs-2367R) at 1:200 followed by conjugated secondary antibody and DAB staining.