bs-2389R [Primary Antibody]
Coxsackie Adenovirus Receptor Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: Coxsackie Adenovirus Receptor

Immunogen Range: 21-120/365


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 1525

Swiss Prot: P78310

Source: KLH conjugated synthetic peptide derived from human Coxsackie Adenovirus Receptor

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Component of the epithelial apical junction complex that may function as an homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with AMICA1/JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, AMICA1 induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
FCM(1:20-100)
IHC-P(1:200-400)
IHC-F(1:100-500)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 38


Cross Reactive Species: Human
Mouse
Rat

Predicted Cross Reactive Species: Dog
Cow
Pig
Horse
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Nande, Rounak Paramjeet, "Investigation Of Ultrasound Targeted Microbubbles As A Therapeutic Gene Delivery System For Prostate Cancer" (2015). Theses, Dissertations and Capstones. Paper 915.Read more>>
  • Wang MJ et al. Baicalin Inhibits Coxsackievirus B3 Replication by Reducing Cellular Lipid Synthesis. Am J Chin Med. 2020;48(1):143-160. Read more>>
  • Mokhashi N et al. Transduction Efficiency of Adenovirus Vectors in Endothelial Cells and Vascular Smooth Muscle Cells. J Cardiovasc Pharmacol. 2020 Jun;75(6):603-607.Read more>>
  • Morio Yamazaki. et al. Soluble JAM-C Ectodomain Serves as the Niche for Adipose-Derived Stromal/Stem Cells. Biomedicines. 2021 Mar;9(3):278Read more>>
  • Jae Won Song. et al. Isolation and Genomic Analysis of Single Circulating Tumor Cell Using Human Telomerase Reverse Transcriptase and Desmoglein-2. 2022 Jan 17Read more>>
VALIDATION IMAGES

Lane 1: rat heart lysates Lane 2: rat embryo lysates probed with Anti Coxsackie Adenovirus Receptor Polyclonal Antibody, Unconjugated (bs-2389R) at 1:200 in 4C. Followed by conjugation to secondary antibody (bs-0295G-HRP) at 1:3000 90min in RT. Predicted band 38kD. Observed band size: 38kD