bs-2418R-A488

DATASHEET

Host: Rabbit

Target Protein: NCR3

Immunogen Range: 81-180/201

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 259197

Swiss Prot: O14931

Source: KLH conjugated synthetic peptide derived from human NCR3

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Cytotoxicity-activating receptor that contributes to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. Engagement of NCR3 by BAG6 also promotes dendritic cell (DC) maturation, both through killing those DCs that did not properly acquire a mature phenotype, and inducing NK cells to release TNFA and IFNG, which promotes DC maturation.

Conjugation: ALEXA FLUOR® 488

Excitation/ Emission: 490nm/525nm

Size: 100ul

Concentration: 1ug/ul

Applications: FCM(1:20-100)

Predicted Molecular Weight: 20

Cross Reactive Species: Human

Predicted Cross Reactive Species: Rat
Dog
Horse
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.