bs-24324R-Biotin

DATASHEET

Host: Rabbit

Target Protein: UBE2Q1

Immunogen Range: 171-270/422

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 55585

Swiss Prot: Q7Z7E8

Source: KLH conjugated synthetic peptide derived from human UBE2Q1:171-270/422

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (UBE1s), ubiquitin-conjugating enzymes (UBE2s), and ubiquitin-protein ligases (UBE3s). When ubiquitin is activated by a UBE1, it is transferred to the cysteine residue on a UBE2. UBE2 then binds a UBE3, which transfers the ubiquitin from the UBE2 cysteine to a lysine residue on the target protein. Ubiquitin-conjugating enzyme E2 Q1 (UBE2Q1), also known as ubiquitin-protein ligase Q1 or ubiquitin carrier protein Q1, is an 422 amino acid protein belonging to the ubiquitin-conjugating enzyme (UBE2) family. Two named isoforms of UBE2Q1 exist as a result of alternative splicing events. Function : Catalyzes the covalent attachment of ubiquitin to other proteins (By similarity). Similarity : Belongs to the ubiquitin-conjugating enzyme family.

Conjugation: Biotin

Excitation/ Emission: N/A

Size: 100ul

Concentration: 1ug/ul

Applications: IHC-P(1:200-400)

Cross Reactive Species: Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.