bs-2453R [Primary Antibody]
CCL17 POLYCLONAL ANTIBODY
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: CCL17

Immunogen Range: 41-103/103


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 20295

Source: KLH conjugated synthetic peptide derived from mouse CCL17

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. TARC displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. TARC binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells.

Size: 100ul

Concentration: 1ug/ul

Applications: ELISA(1:500-1000)
IHC-P(1:200-400)
IHC-F(1:100-500)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 8


Cross Reactive Species: Mouse

Predicted Cross Reactive Species: Human
Rat

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Nakamura, Kiwamu, et al. "Orosomucoid 1 drives opportunistic infections through the polarization of monocytes to the M2b phenotype." Cytokine 73.1 (2015): 8-15.Read more>>
  • Chen, Yi-Lien, and Bor-Luen Chiang. "Targeting TSLP With shRNA Alleviates Airway Inflammation and Decreases Epithelial CCL17 in a Murine Model of Asthma." Molecular Therapy—Nucleic Acids 5.5 (2016): e316.Read more>>
  • Hou DD et al. Anti-inflammatory effects of quercetin in a mouse model of MC903-induced atopic dermatitis. Int Immunopharmacol. 2019 Jun 7;74:105676.Read more>>
  • Dian-Dong Hou. et al. Therapeutic effects of myricetin on atopic dermatitis in vivo and in vitro. PHYTOMEDICINE. 2022 Jul;102:1542Read more>>
  • Zhiyu Zhang. et al. CCL17 blockade by CCL17mAb/GSK-J4 ameliorates hyperalgesia in a rat model of postoperative pain. BIOL PHARM BULL. 2023 Feb 15Read more>>
VALIDATION IMAGES

Formalin-fixed and paraffin embedded mouse brain tissue labeled with Anti-CCL17/ABCD2 Polyclonal Antibody, Unconjugated (bs-2453R) followed by conjugation to the secondary antibody