bs-2471R [Primary Antibody]
ICOS-L/B7-H2/CD275 Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: ICOS-L/B7-H2/CD275

Immunogen Range: 19-120/302


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 23308

Swiss Prot: O75144

Source: KLH conjugated synthetic peptide derived from Rat ICOS-L

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function (By similarity).

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
FCM(1:20-100)

Predicted Molecular Weight: 34


Cross Reactive Species: Human
Mouse

Predicted Cross Reactive Species: Rat

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Ma et al. Effect of follicular helper T cells on the pathogenesis of asthma. (2017) Exp.Ther.Me. 14:967-972Read more>>
VALIDATION IMAGES

Lane 1: Human Daudi cell lysates; Lane 2: Human HL-60 cell lysates; Lane 3: Human JAR cell lysates probed with ICOS ligand Polyclonal Antibody, Unconjugated (bs-2471R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at room temperature for 60 min.