bs-2548R-RBITC [Conjugated Primary Antibody]
CXCL4/PF4 Polyclonal Antibody, RBITC Conjugated
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Host: Rabbit

Target Protein: CXCL4/PF4

Immunogen Range: 55-95/101


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 5196

Swiss Prot: P02776

Source: KLH conjugated synthetic peptide derived from human CXCL4/PF4

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form.

Conjugation: RBITC

Excitation/ Emission: 570nm/595nm

Size: 100uL

Concentration: 1ug/ul

Applications: WB(1:500-2000)

Predicted Molecular Weight: 11


Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Hwaiz et al. Platelet secretion of CXCL4 is Rac1-dependent and regulates neutrophil infiltration and tissue damage in septic lung damage. (2015) Br.J.Pharmaco. 172:5347-59Read more>>