bs-2579R-Cy5.5

DATASHEET

Host: Rabbit

Target Protein: Granzyme D/B/E/N/G/F/H

Immunogen Range: 151-252/252

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 2999

Source: KLH conjugated synthetic peptide derived from human Granzyme D/B/E/N/G/F/H

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

protease required for lymphocyte cytotoxic granules to lyse target cells [RGD]. Granzyme B is a cysteine protease found in the cytoplasmic lysosome-like granules of cytolytic T lymphocytes (CTL) and natural killer (NK) cells and is is required for the induction of target cell lysis. This occurs as part of cell mediated immune responses, and can activate apoptosis in target cells by both caspase dependent and caspase independent mechanisms.

Conjugation: Cy5.5

Excitation/ Emission: 675nm/694nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)

Predicted Molecular Weight: 28

Predicted Cross Reactive Species: Human
Mouse
Rat
Dog
Cow
Pig
Horse

For research use only. Not intended for diagnostic or therapeutic use.