bs-2604R [Primary Antibody]
IL12RB2 Polyclonal Antibody
www.biossusa.com
support@biossusa.com
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: IL12RB2

Immunogen Range: 301-400/862


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 3595

Swiss Prot: Q99665

Source: KLH conjugated synthetic peptide derived from human IL-12RB2

Purification: purified by Protein A.

Storage Buffer: 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

Receptor for interleukin-12. This subunit is the signaling component coupling to the JAK2/STAT4 pathway. Promotes the proliferation of T-cells as well as NK cells. Induces the promotion of T-cells towards the Th1 phenotype by strongly enhancing IFN-gamma production.

Size: 100ul

Concentration: 1mg/ml

Applications: WB(1:500-2000)
ELISA(1:5000-10000)

Predicted Molecular Weight: 95 kDa


Cross Reactive Species: Human

Predicted Cross Reactive Species: Mouse

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Yusong Miao. et al. Mycoplasma gallisepticum induced inflammation-mediated Th1/Th2 immune imbalance via JAK/STAT signaling pathway in chicken trachea: Involvement of respiratory microbiota. Vet Microbiol. 2022 Feb;265:10933Read more>>
  • Jose Rosas Almanza. et al. IL-12p40 promotes secondary damage and functional impairment after spinal cord contusional injury. J NEUROSCI RES. 2022 SepRead more>>
  • Kexin Wang. et al. Lactobacillus salivarius ameliorates Mycoplasma gallisepticum-induced inflammation via the JAK/STAT signaling pathway involving respiratory microbiota and metabolites. POULTRY SCI. 2024 Jun;:103942Read more>>
VALIDATION IMAGES

Lane 1: Human A549 cell lysates; Lane 2: Human Hela cell lysates probed with IL12RB2 Polyclonal Antibody, Unconjugated (bs-2604R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.