bs-2616R [Primary Antibody]
IL-18R Beta/CD218b Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: IL-18R Beta/CD218b

Immunogen Range: 15-120/599

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 8807

Swiss Prot: O95256

Source: KLH conjugated synthetic peptide derived from human IL-18R beta

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.

Storage Condition: Store at -20°C for 12 months..

Background: Required for the high affinity binding of interleukin 18 (IL-18) to its receptor complex (By similarity). Together with IL18R1 mediates IL-18-dependent activation of NF-kappa-B and JNK.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-1000)
ELISA(1:500-1000)
FCM(1:20-100)
IP(1-2ug)

Cross Reactive Species: Human
Mouse

Predicted Cross Reactive Species: Rat
Dog
Horse

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Valente, Anthony J., et al. "Interleukin-18 enhances IL-18R/Nox1 binding, and mediates TRAF3IP2-dependent smooth muscle cell migration. Inhibition by simvastatin." Cellular Signalling (2013).Read more>>
  • Kobori et al. Interleukin-18 Amplifies Macrophage Polarization and Morphological Alteration, Leading to Excessive Angiogenesis. (2018) Front.Immunol. 9:334Read more>>
  • Valente et al. Interleukin-18 enhances IL-18R/Nox1 binding, and mediates TRAF3IP2-dependent smooth muscle cell migration. Inhibition by simvastatin. (2013) Cell.Signal. 25:1447-56Read more>>
  • Dou Y et al. The Riemerella anatipestifer M949_RS01035 gene is involved in bacterial lipopolysaccharide biosynthesis. Vet. Res. (2018) Sep 17 ;49(1)Read more>>
VALIDATION IMAGES

Mouse spleen lysates probed with IL-18R Beta Polyclonal Antibody, Unconjugated (bs-2616R) at 1:300 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.