bs-2655R-A647 [Conjugated Primary Antibody]
LTB4-R2 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated
www.biossusa.com
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DATASHEET

Host: Rabbit

Target Protein: LTB4-R2

Immunogen Range: 25-120/389


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 56413

Swiss Prot: Q9NPC1

Source: KLH conjugated synthetic peptide derived from human LTB4-R2

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3.

Conjugation: ALEXA FLUOR® 647

Excitation/ Emission: 650nm/665nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
FCM(1:20-100)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 41


Cross Reactive Species: Mouse
Rat

Predicted Cross Reactive Species: Human
Dog
Cow
Pig
Guinea Pig

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Wculek, S. Pre-metastatic neutrophils directly support highly tumourigenic breast cancer cells during lung metastasis via a leukotriene-ERK1/2 axis. Diss. UCL (University College London), 2016.Read more>>
  • Zinn, Sebastian, et al. "The leukotriene B4 receptors BLT1 and BLT2 form an antagonistic sensitizing system in peripheral sensory neurons." Journal of Biological Chemistry (2017): jbc-M116.Read more>>
  • Brandt et al. Excessive localized leukotriene B4 levels dictate poor skin host defense in diabetic mice. (2018) JCI.Insight. 3 Read more>>
VALIDATION IMAGES