bs-2695R [Primary Antibody]
CD265 Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: CD265

Immunogen Range: 51-150/616


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 8792

Swiss Prot: Q9Y6Q6

Source: KLH conjugated synthetic peptide derived from human CD265

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis. Involved in the regulation of interactions between T-cells and dendritic cells.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
FCM(1:20-100)
IHC-P(1:200-400)
IHC-F(1:100-500)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 63-70


Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Gao FP et al. Au Clusters Treat Rheumatoid Arthritis with Uniquely Reversing Cartilage/Bone Destruction. Adv. Sci. 2019, 1801671.Read more>>
  • Li L et al. Janus kinase inhibitor ruxolitinib blocks thymic regeneration after acute thymus injury. Biochem Pharmacol. 2019 Nov 11;171:113712.Read more>>
  • Yuan L et al. La2O3 Nanoparticles Induce Reproductive Toxicity Mediated by the Nrf-2/ARE Signaling Pathway in Kunming Mice. Int J Nanomedicine. 2020 May 14;15:3415-3431.Read more>>
  • Teng X et al. Effects of Low Dietary Phosphorus on Tibia Quality and Metabolism in Caged Laying Hens. Prev Vet Med. 2020 Aug;181:105049.Read more>>
  • Francesca Punzoet al. Can Denosumab be used in combination with Doxorubicin in Osteosarcoma?. Oncotarget. 2020 Jul 14;11(28):2763-2773.Read more>>
  • Hongyi Qu. et al. The effects of vasoactive intestinal peptide on RANKL-induced osteoclast formation. Ann Transl Med. 2021 Jan; 9(2): 127Read more>>
  • Qianwen Lv. et al. Effects of lentinan on NF?B activity in the liver of burn rats with sepsis. Exp Ther Med. 2020 Sep;20(3):2279-2283Read more>>
  • Cao Lu. et al. Exploring the Action Mechanism of the Active Ingredient of Quercetin in Ligustrum lucidum on the Mouse Mastitis Model Based on Network Pharmacology and Molecular Biology Validation. EVID-BASED COMPL ALT. 2022;2022:4236222Read more>>
  • Ye Jin. et al. Fluoride-induced osteoporosis via interfering with the RANKL/RANK/OPG pathway in ovariectomized rats: Oophorectomy shifted skeletal fluorosis from osteosclerosis to osteoporosis. ENVIRON POLLUT. 2023 Nov;336:122407Read more>>
VALIDATION IMAGES

L1 rat heart, L2 rat brain lysates probed (bs-2695R) at 1:200 in 4˚C. Followed by conjugation to secondary antibody (bs-0295G-HRP) at 1:3000 90min in RT. Predicted and observed band size: 65kDa.


Lane 1: Mouse Lung lysates probed with RANK/CD265 Polyclonal Antibody, Unconjugated (bs-2695R) at 1:1000 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.