Host: Rabbit
Target Protein: TREM2
Immunogen Range: 1-100/230
Clonality: Polyclonal
Isotype: IgG
Entrez Gene: 54209
Swiss Prot: Q9NZC2
Source: KLH conjugated synthetic peptide derived from human TREM2
Purification: Purified by Protein A.
Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Background:
Conjugation: FITC
Excitation/ Emission: 494nm/518nm
Size: 100ul
Concentration: 1ug/ul
Applications:
WB(1:300-5000)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)
Predicted Molecular Weight: 25
Cross Reactive Species:
Human
Mouse
Rat
Pig
Predicted Cross Reactive Species:
Dog
Cow
Horse
For research use only. Not intended for diagnostic or therapeutic use.
- Satoh, Jun-ichi, et al. "A survey of TREM2 antibodies reveals neuronal but not microglial staining in formalin-fixed paraffin-embedded postmortem Alzheimer's brain tissues." Alzheimer's research & therapy 5.4 (2013): 30.Read more>>
- Rai et al. Vitamin D attenuates inflammation, fatty infiltration, and cartilage loss in the knee of hyperlipidemic microswine. (2016) Arthritis.Res.The. 18:203Read more>>
- Li et al. TREM2 inhibits inflammatory responses in mouse microglia by suppressing the PI3K/NF-κB signaling. (2018) Cell.Biol.Int. Apr 16.Read more>>
- Elizabeth Olmsted-Davis. et al. A Population of M2 Macrophages Associated With Bone Formation. Front Immunol. 2021; 12: 686769Read more>>
- Dai Shi. et al. Synthesis and Evaluation of 68Ga-NOTA-COG1410 Targeting to TREM2 of TAMs as a Specific PET Probe for Digestive Tumor Diagnosis. Anal Chem. 2022;94(9):3819383Read more>>
- Ke Wu. et al. The microglial innate immune receptors TREM-1 and TREM-2 in the anterior cingulate cortex (ACC) drive visceral hypersensitivity and depressive-like behaviors following DSS-induced colitis. BRAIN BEHAV IMMUN. 2023 JuRead more>>
- Cheng Wenchao. et al. The Impact of Dipyridamole on Disease-Associated Microglia Phenotypic Transformation in White Matter Lesions Induced by Chronic Cerebral Hypoperfusion. NEUROCHEM RES. 2023 Dec;:1-14Read more>>