DATASHEET
Host:
Rabbit
Target Protein:
GSTp1
Specificity:
GSTp2 in mouse
Immunogen Range:
121-210/210
Clonality:
Polyclonal
Isotype:
IgG
Entrez Gene:
14870
Swiss Prot:
P19157
Source:
KLH conjugated synthetic peptide derived from Mouse GstP1
Purification:
Purified by Protein A.
Storage Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Background:
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Can metabolize 1-chloro-2,4-dinitrobenzene. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration (By similarity).
PRODUCT SPECIFIC PUBLICATIONS
- Zhang, Fu, et al. "Up-regulation of protein tyrosine nitration in methamphetamine-induced neurotoxicity through DDAH/ADMA/NOS pathway." Neurochemistry International (2013).Read more>>
- Li, Hongyan, et al. "Differential proteome and gene expression reveal response to carbon ion irradiation in pubertal mice testes." Toxicology Letters (2014).Read more>>
- Zhang, Chunlei, et al. "Insights into the Distinguishing Stress-induced Cytotoxicity of Chiral Gold Nanoclusters and the Relationship with GSTP1." TheranosticsRead more>>
- Lin et al. Penehyclidine Hydrochloride Preconditioning Provides Cardioprotection in a Rat Model of Myocardial Ischemia/Reperfusion Injury. (2015) PLoS.One. 10:e0138051Read more>>
- Jiang et al. Scavenger receptor-C acts as a receptor for Bacillus thuringiensis vegetative insecticidal protein Vip3Aa and mediates the internalization of Vip3Aa via endocytosis. (2018) PLoS.Pathog. 14:e1007347Read more>>
VALIDATION IMAGES
Formalin-fixed and paraffin embedded human kidney labeled with Anti-GST Polyclonal Antibody, Unconjugated (bs-2735R) at 1:200 followed by conjugation to the secondary antibody and DAB staining
Mouse splenocytes probed with Rabbit Anti-GST Polyclonal Antibody, Unconjugated (bs-2735R) (green) at 1:100 for 30 minutes followed by a FITC conjugated secondary antibody compared to unstained cells (blue), secondary only(light blue), and isotype control(orange).