DATASHEET
Host:
Rabbit
Target Protein:
Aurora A
Clonality:
Polyclonal
Isotype:
IgG
Entrez Gene:
6790
Source:
KLH conjugated synthetic peptide derived from human Auroa A
Purification:
Purified by Protein A.
Storage Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Store at -20°C for 12 months.
Background:
Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.
PRODUCT SPECIFIC PUBLICATIONS
- Ruoyang Lin. et al. Inhibitory Effects of Rabdosia rubescens in Esophageal Squamous Cell Carcinoma: Network Pharmacology and Experimental Validation. EVID-BASED COMPL ALT. 2022 Nov 10;2022:2696347Read more>>
- Qinbing Xue. et al. Lycorine (Lycoris radiata)a unique natural medicine on breast cancer. J CELL MOL MED. 2024 Aug;28(16):e70032Read more>>
VALIDATION IMAGES
Formalin-fixed and paraffin embedded human ovarian carcinoma labeled with Anti-Aurora A/ARK-1/AURKA Polyclonal Antibody, Unconjugated (bs-2749R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.
Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-Aurora A/ARK-1/AURKA Polyclonal Antibody, Unconjugated (bs-2749R) at 1:200 followed by conjugation to the secondary antibody and DAB staining