bs-2791R-RBITC [Conjugated Primary Antibody]
CRHR1 Polyclonal Antibody, RBITC Conjugated
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Host: Rabbit

Target Protein: CRHR1

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 1394

Source: KLH conjugated synthetic peptide derived from human CRHR1/CRFR1

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

This gene encodes a G-protein coupled receptor that binds neuropeptides of the corticotropin releasing hormone family that are major regulators of the hypothalamic-pituitary-adrenal pathway. The encoded protein is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress, reproduction, immune response and obesity. Alternative splicing results in multiple transcript variants one of which is a non-coding read-through transcript with the neighboring gene MGC57346.

Conjugation: RBITC

Excitation/ Emission: 570nm/595nm

Size: 100uL

Concentration: 1ug/ul

Applications: WB(1:500-2000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Zhu, Xiaoxia, et al. "Xiao Yao San improves depressive-like behavior in rats through modulation of β-arrestin 2 mediated pathways in hippocampus." Evid Based Complement Alternat Med.2014:902516Read more>>
  • Harlé,et al.Murine splenic B cells express corticotropin-releasing hormone receptor 2 that affect their viability during a stress response.(2018) Scientific Reports. 8:143.Read more>>
  • Hashimoto,et al.The Effect of a High-Fat Diet on the Development of Abdominal Aortic Aneurysm in a Vascular Hypoperfusion-Induced Animal Model.(2018) Journal of Vascular Research. 55:63-74.Read more>>
  • Harlé et al. Murine splenic B cells express corticotropin-releasing hormone receptor 2 that affect their viability during a stress response. (2018) Sci.Rep. 8:143Read more>>
  • Junlong Li. et al. Orcinol glucoside improves the depressive-like behaviors of perimenopausal depression mice through modulating activity of hypothalamicCpituitaryCadrenal/ovary axis and activating BDNF- TrkB-CREB signaling pathway. 2021 Aug 11Read more>>