bs-2919R [Primary Antibody]
ACTR Polyclonal Antibody
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Host: Rabbit

Target Protein: ACTR

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 8202

Source: KLH conjugated synthetic peptide derived from human ATR/ACTR

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Ataxia Telangiectasia Mutated (ATM) and Rad 3-related protein (ATR) is a phosphatidylinositol kinase (PK)-related kinase which functions in response to DNA damage and repair as well as at DNA replication checkpoints during the cell cycle. ATR is a member of the DNA-PK kinases closely related to ATM and DNA-PK for which DNA stimulates the observed kinase activity. Chromosomal remodeling proteins have also been reported to associate with ATR complexes. Several known components of the NuRD complex including histone deacetylase 1 (HDAC1), HDAC2, and CHD4.

Size: 100µL

Concentration: 1ug/ul

Applications: IHC-P(1:200-400)
IF(IHC-P)(1:50-200)

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Jun Li. et al. In silico studies reveal the anti-osteosarcoma targets and action mechanisms of resveratrol. PROCESS BIOCHEM. Process Biochem. 2022 Jun;117:191Read more>>
VALIDATION IMAGES

Formalin-fixed and paraffin embedded human lung carcinoma labeled with Rabbit Anti ATR/ACTR/RAC3 Polyclonal Antibody, Unconjugated (bs-2919R) at 1:200 followed by conjugation to the secondary antibody and DAB staining