bs-3148R-A555 [Conjugated Primary Antibody]
GSK-3 Beta(Thr390) Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated
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Host: Rabbit

Target Protein: GSK-3 Beta Thr390

Modification Site: Thr390

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 2932

Source: KLH conjugated Synthesised phosphopeptide derived from human GSK-3 Beta around the phosphorylation site of Thr390

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Glycogen synthase kinase 3 (GSK3) is a proline directed serine threonine kinase that was initially identified as a phosphorylating and inactivating glycogen synthase. GSK3 has been implicated in fundamental cell processes such as cell fate determination, metabolism, transcriptional control and oncogenesis. Two isoforms, alpha (GSK3A; OMIM 606784) and beta, show a high degree of amino acid homology within their catalytic domains. GSK3B is involved in energy metabolism, neuronal cell development and body pattern formation.

Conjugation: ALEXA FLUOR® 555

Excitation/ Emission: 555nm/580nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
FCM(1:20-100)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 47


Cross Reactive Species: Human
Rat

Predicted Cross Reactive Species: Dog
Pig
Chicken
Rabbit
Guinea Pig

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • van Rees, Geertje Frederique, et al. "Evidence of microglial activation following exposure to serum from first-onset drug-naïve schizophrenia patients." Brain, Behavior, and Immunity (2017).Read more>>
VALIDATION IMAGES