bs-3181R-A488

DATASHEET

Host: Rabbit

Target Protein: HSP90 alpha Thr5 + Thr7

Specificity: These phosphorylation sites are homologous across the listed species.

Modification Site: Thr5 + Thr7

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 3320

Swiss Prot: P07900

Source: KLH conjugated synthetic phosphopeptide derived from human HSP90 around the phosphorylation site of Thr5/7

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes.

Conjugation: ALEXA FLUOR® 488

Excitation/ Emission: 490nm/525nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 84

Cross Reactive Species: Human
Mouse

Predicted Cross Reactive Species: Rat
Pig
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.