bs-3295R-RBITC

DATASHEET

Host: Rabbit

Target Protein: Phospho-MYL (Ser19)

Modification Site: Ser19

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 5371

Source: KLH conjugated synthetic phosphopeptide derived from human MYL2 around the phosphorylation site of Ser19

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Myosin light chain (MLC) is a subunit of the conventional myosins (e.g. myosin II). In smooth muscle and non-muscle cells conventional myosins mediate a wide variety of contractile events including cytokinesis, cell motility, and smooth muscle contraction. MLC is phosphorylated by multiple serine-threonine kinases such as Rho-kinase and PAK, however myosin light chain kinase (MLCK) acts as the primary kinase. Contractile activity of conventional myosins is regulated by phosphorylation of MLC on several residues.

Conjugation: RBITC

Excitation/ Emission: 570nm/595nm

Size: 100µL

Concentration: 1ug/ul

Applications: WB(1:300-5000)
IF(1:50-200)

Cross Reactive Species: Mouse

For research use only. Not intended for diagnostic or therapeutic use.