bs-33272P

DATASHEET

Entrez Gene: 87

Swiss Prot: P12814

Source: Recombinant human Alpha-actinin-1 protein is expressed in E.coli with C-His. It contains the amino acid sequence 1-205/377

Storage Buffer: 0.01M TBS(pH7.4)

Storage: The product should be stored at -70°C or -20°C.

Background:

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Sequence: 1-205/377

Size: 100µg, 500µg, 20µg

Applications: Others

Mol. Wt.: 68

Species: Others

For research use only. Not intended for diagnostic or therapeutic use.