bs-34032R [Primary Antibody]
VEGF Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: VEGF

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 7422

Swiss Prot: P15692

Source: KLH conjugated synthetic peptide derived from human VEGF

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)

Predicted Molecular Weight: 24


Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Jingxin Ding. et al. Regulated contribution of local and systemic immunity to new bone regeneration by modulating B/Sr concentration of bioactive borosilicate glass. MATER TODAY BIO. 2023 Apr;19:100585Read more>>
  • Yixin Xia. et al. Regulation of endothelial cells on the osteogenic ability of bone marrow mesenchymal stem cells in peri-implantitis. TISSUE CELL. 2023 Apr;81:102042Read more>>
  • Lei Yuan. et al. Sambucus adnata Polysaccharide SPS-1 Inhibits Growth of Transplanted Lung Cancer via Polarizing Tumor Associated Macrophage From M2 into M1. NAT PROD COMMUN. ;()Read more>>
  • Lubin Zhou. et al. A Novel Self-Pumping Janus Dressing for Promoting Wound Immunomodulation and Diabetic Wound Healing. ADV HEALTHC MATER. 2023 Nov;:230346Read more>>
VALIDATION IMAGES

Lane 1: Human Huvec cell lysates; Lane 2: Human HepG2 cell lysates; Lane 3: Human U251 cell lysates; Lane 4: Human THP-1 cell lysates ; Lane 5: Human A431 cell lysates;Lane 6: Human U87MG cell lysates; Lane 7: Human Hela cell lysates; Lane 8: Human Jurkat cell lysates; Lane 9: Human MCF-7 cell lysates probed with VEGF Polyclonal Antibody, Unconjugated (bs-34032R) at 1:1000 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.