bs-3577R-Cy5 [Conjugated Primary Antibody]
SLC11A2 Polyclonal Antibody, Cy5 Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: SLC11A2

Immunogen Range: 251-350/568


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 4891

Swiss Prot: P49281

Source: KLH conjugated synthetic peptide derived from human SLC11A2

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Important in metal transport, in particular iron. Can also transport manganese, cobalt, cadmium, nickel, vanadium and lead. Involved in apical iron uptake into duodenal enterocytes. Involved in iron transport from acidified endosomes into the cytoplasm of erythroid precursor cells. May play an important role in hepatic iron accumulation and tissue iron distribution. May serve to import iron into the mitochondria.

Conjugation: Cy5

Excitation/ Emission: 625,650nm/670nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
FCM(1:20-100)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 62


Cross Reactive Species: Human
Mouse
Rat
Chicken

Predicted Cross Reactive Species: Cow

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Zhang, L. Y., et al. "Effect of iron source on iron absorption and gene expression of iron transporters in the ligated duodenal loops of broilers." Journal of Animal Science (2017).Read more>>
  • Qian Wang. et al. Efficient iron utilization compensates for loss of extracellular matrix of ovarian cancer spheroids. Free Radical Bio Med. 2021 Feb;164:369Read more>>
  • Zhang Hongxia. et al. Hepcidin Promoted Ferroptosis through Iron Metabolism which Is Associated with DMT1 Signaling Activation in Early Brain Injury following Subarachnoid Hemorrhage. Oxid Med Cell Longev. 2021;2021:9800794Read more>>
  • Song, Yanqiu. et al. Iron overload impairs renal function and is associated with vascular calcification in rat aorta. BIOMETALS. 2022 Sep;:1-15Read more>>
  • Limin Shi. et al. FoxO1 regulates adipose transdifferentiation and iron influx by mediating Tgf1 signaling pathway. REDOX BIOL. 2023 Jul;63:102727Read more>>
  • Yang Liu. et al. Inhibition of Oxidative Stress-Induced Ferroptosis Can Alleviate Rheumatoid Arthritis in Human. J IMMUNOL RES. 2024;2024:9943747Read more>>
VALIDATION IMAGES