bs-3579R [Primary Antibody]
SLC40A1 Polyclonal Antibody
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Host: Rabbit

Target Protein: SLC40A1

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 30061

Source: KLH conjugated synthetic peptide derived from human SLC40A1

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

SLC40A1 may be involved in iron export from duodenal epithelial cells and also in transfer of iron between maternal and fetal circulation. It mediates iron efflux in the presence of a ferroxidase (hephaestin and/or ceruloplasmin). Defects in SLC40A1 are the cause of hemochromatosis type 4, an autosomal dominant iron-loading disorder characterized by early iron accumulation in reticuloendothelial cells and a marked increase in serum ferritin.

Size: 100µL

Concentration: 1ug/ul

Applications: WB(1:300-5000)
IHC-P(1:200-400)
IF(IHC-P)(1:50-200)

Cross Reactive Species: Human

Predicted Cross Reactive Species: Mouse
Rat
Dog
Cow
Pig
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Liu et al. Synthetic Porcine Hepcidin Exhibits Different Roles in Escherichia coli and Salmonella Infections. (2017) Antimicrob.Agents.Chemother.Sep 22;61(10).Read more>>
  • Zhang J et al. Iron Dyshomeostasis Participated in Rat Hippocampus Toxicity Caused by Aluminum Chloride. Biol Trace Elem Res. 2019 Dec 17. Read more>>
  • Yuan Zhao. et al. Chlorogenic Acid Alleviates Chronic Stress-Induced Duodenal Ferroptosis via the Inhibition of the IL-6/JAK2/STAT3 Signaling Pathway in Rats. J AGR FOOD CHEM. J Agr Food Chem. 2022;XXXX(XXX):XXX-XXXRead more>>
  • Yu-Sheng Shi. et al. Dendrobine rescues cognitive dysfunction in diabetic encephalopathy by inhibiting ferroptosis via activating Nrf2/GPX4 axis. PHYTOMEDICINE. 2023 Jul;:154993Read more>>
  • Xiaokang Zhu. et al. A multi-mode Rhein-based nano-platform synergizing ferrotherapy/chemotherapy-induced immunotherapy for enhanced tumor therapy. ACTA BIOMATER. 2024 ApRead more>>
VALIDATION IMAGES

Formalin-fixed and paraffin embedded human placenta labeled with Rabbit Anti SLC40A1 Polyclonal Antibody, Unconjugated (bs-3579R) at 1:200 followed by conjugation to the secondary antibody and DAB staining


Formalin-fixed and paraffin embedded rat colitis labeled with Rabbit Anti SLC40A1 Polyclonal Antibody, Unconjugated (bs-3579R) at 1:200 followed by conjugation to the secondary antibody and DAB staining