bs-3654R-Biotin [Conjugated Primary Antibody]
FPRL1 Polyclonal Antibody, Biotin Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: FPRL1/Lipoxin A4 receptor

Immunogen Range: 51-150/351


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 2358

Swiss Prot: P25090

Source: KLH conjugated synthetic peptide derived from human FPRL1

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4).

Conjugation: Biotin

Excitation/ Emission: N/A

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)

Predicted Molecular Weight: 39


Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Diao, Na, et al. "Deficiency in Toll-interacting protein (Tollip) skews inflamed yet incompetent innate leukocytes in vivo during DSS-induced septic colitis."Scientific Reports 6 (2016): 34672.Read more>>
  • Wang et al. Formylpeptide Receptors Promote the Migration and Differentiation of Rat Neural Stem Cells. (2016) Sci.Re. 6:25946Read more>>
  • Hebeda CB et al. Annexin A1/Formyl Peptide Receptor Pathway Controls Uterine Receptivity to the Blastocyst. Cells. 2020 May 11;9(5):1188.Read more>>
  • Wenzheng Xia. et al. ANXA1 directs Schwann cells proliferation and migration to accelerate nerve regeneration through the FPR2/AMPK pathway. Faseb J. 2020 Oct;34(10):13993-14005Read more>>
  • Cao Yirui. et al. Formyl peptide receptor 2 activation by mitochondrial formyl peptides stimulates the neutrophil proinflammatory response via the ERK pathway and exacerbates ischemiaCreperfusion injury. CELL MOL BIOL LETT. 2023 Dec;28(1):1-24Read more>>
  • Yang Fan. et al. Identifying oxidative stress-related biomarkers in idiopathic pulmonary fibrosis in the context of predictive, preventive, and personalized medicine using integrative omics approaches and machine-learning strategies. EPMA Journal. 2023 Jul;:1-26Read more>>
  • Hiram Roddy. et al. An inflammation resolution-promoting intervention prevents atrial fibrillation due to left-ventricular dysfunction. CARDIOVASC RES. 2023 DecRead more>>