DATASHEET
Host:
Rabbit
Target Protein:
Neurogenin 2/NGN2
Clonality:
Polyclonal
Isotype:
IgG
Entrez Gene:
63973
Source:
KLH conjugated synthetic peptide derived from human Neurogenin 2
Purification:
Purified by Protein A.
Storage Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage:
Store at -20°C for 12 months.
Background:
Neurogenin 2 is a helix-loop-helix class of transcription factor. Transcription factors with bHLH motifs modulate critical events in the development of the mammalian neocortex. The transition from proliferation to neurogenesis involves a coordinate increase in the activity of proneural bHLH factors, including Neurogenin 2 and a decrease in the activity of Hes and Id factors. bHLH factors have key roles in corticogenesis, affecting the timing of differentiation and the specification of cell fate.
VALIDATION IMAGES
Formalin-fixed and paraffin embedded rat brain labeled with Anti-Neurogenin 2/NGN2 Polyclonal Antibody, Unconjugated (bs-3692R) at 1:200 followed by conjugation to the secondary antibody and DAB staining
Lane 1: Mouse Cerebrum tissue lysates; Lane 2: Mouse Spleen tissue lysates probed with Neurogenin 2 Polyclonal Antibody, Unconjugated (bs-3692R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at room temperature for 60 min.