bs-3816R-PerCP-Cy7 [Conjugated Primary Antibody]
Oct-4B/OCT4B-190 Polyclonal Antibody, PerCP-Cy7 Conjugated
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Host: Rabbit

Target Protein: Oct-4B/OCT4B-190

Immunogen Range: 201-300/360


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 5460

Swiss Prot: Q01860

Source: KLH conjugated synthetic peptide derived from human OCT4B-190

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.

Background:

Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP26. Critical for early embryogenesis and for embryonic stem cell pluripotency.

Conjugation: PerCP-Cy7

Excitation/ Emission: 482nm/780nm

Size: 100uL

Concentration: 1ug/ul

Applications: WB(1:500-2000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)

Predicted Molecular Weight: 21/39


Cross Reactive Species: Mouse
Rat

Predicted Cross Reactive Species: Human
Dog
Cow
Pig

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Liu, Yu-Hong, et al. "A signature for induced pluripotent stem cell?Cassociated genes in colorectal cancer."Medical Oncology 30.1 (2013): 1-11.eRead more>>
  • Darabi, Shahram, et al. "Polarized neural stem cells derived from adult bone marrow stromal cells develop a rosette-like structure." In Vitro Cellular & Developmental Biology-Animal (2013): 1-15.Read more>>
  • Tanabe, A., et al. "Radioresistance of cancer stem‐like cell derived from canine tumours." Veterinary and Comparative Oncology (2014).Read more>>
  • Liu, Lu, et al. "OCT4B1 Regulates the Cellular Stress Response of Human Dental Pulp Cells with Inflammation." BioMed Research International 2017 (2017).Read more>>
  • Liu et al. JNK is required for maintaining the tumor-initiating cell-like properties of acquired chemoresistant human cancer cells. (2015) Acta.Pharmacol.Si. 36:1099-106Read more>>
  • Liu et al. OCT4B1 Regulates the Cellular Stress Response of Human Dental Pulp Cells with Inflammation. (2017) Biomed.Res.Int. 2017:2756891Read more>>
  • Xiuxiu Liu. et al. PHF20 inhibition promotes apoptosis and cisplatin chemosensitivity via the OCT4?p?STAT3?MCL1 signaling pathway in hypopharyngeal squamous cell carcinoma. Int J Oncol. 2021 Jul;59(1):1-14Read more>>
  • Jiejuan Lai. et al. Comparison of the biological and functional characteristics of mesenchymal stem cells from intrahepatic and identical bone marrow. Stem Cell Res. 2021 Aug;55:102477Read more>>
VALIDATION IMAGES