bs-3879R-Cy3 [Conjugated Primary Antibody]
Cytochrome b245 Light Chain Antibody, Cy3 Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: Cytochrome b245 Light Chain

Immunogen Range: 21-120/195


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 1535

Swiss Prot: P13498

Source: KLH conjugated synthetic peptide derived from human CK18 Cytochrome b245 Light Chain/p22phox

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.

Conjugation: Cy3

Excitation/ Emission: 512,550nm/570,615nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 21


Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Walton, Noah M., et al. "Adult neurogenesis transiently generates oxidative stress." PloS one 7.4 (2012): e35264.Read more>>
  • Li, A., et al. "Arctigenin suppresses transforming growth factor-β1-induced expression of monocyte chemoattractant protein-1 and the subsequent epithelial-mesenchymal transition through reactive oxygen species-dependent ERK/NF-κB signaling pathway in renal tubular epithelial cells." Free Radical Research (2015): 1-19.Read more>>
  • Yue, Long, et al. "Bletilla striata polysaccharide inhibits angiotensin II-induced ROS and inflammation via NOX4 and TLR2 pathways." International Journal of Biological Macromolecules (2016).Read more>>
  • Yoshida, Toshinori, et al. "Apocynin and enzymatically modified isoquercitrin suppress the expression of a NADPH oxidase subunit p22phox in steatosis-related preneoplastic liver foci of rats." Experimental and Toxicologic Pathology (2016).Read more>>
  • Song Q et al. Potential mechanisms underlying the protective effects of salvianic acid A against atherosclerosis in vivo and vitro. (2019)Biomedicine & Pharmacotherapy, 109, 945–956. Read more>>
  • Xiaoyu Liu. et al. Geniposide Combined With Notoginsenoside R1 Attenuates Inflammation and Apoptosis in Atherosclerosis via the AMPK/mTOR/Nrf2 Signaling Pathway. Front Pharmacol. 2021; 12: 687394Read more>>
  • Xin Guo. et al. Aspirin protects human trophoblast HTR-8/SVneo cells from H2O2-Induced oxidative stress via NADPH/ROS pathway. PLACENTA. 2023 Dec;144:55Read more>>
VALIDATION IMAGES