bs-3909R-Cy3 [Conjugated Primary Antibody]
Megalin Polyclonal Antibody, Cy3 Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: Lrp2/Megalin

Immunogen Range: 3401-3500/4655


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 4036

Swiss Prot: P98164

Source: KLH conjugated synthetic peptide derived from human Megalin

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Acts together with cubilin to mediate HDL endocytosis (By similarity). May participate in regulation of parathyroid-hormone and para-thyroid-hormone-related protein release.

Conjugation: Cy3

Excitation/ Emission: 512,550nm/570,615nm

Size: 100ul

Concentration: 1ug/ul

Applications: FCM(1:20-100)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 519


Cross Reactive Species: Human
Mouse

Predicted Cross Reactive Species: Rat
Dog
Horse
Chicken
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Jayachandran, Muthuvel, et al. "Extracellular vesicles in urine of women with but not without kidney stones manifest patterns similar to men: a case control study." Biol Sex Differ 6.2 (2015).Read more>>
  • Erikci, Acelya, Gulberk Ucar, and Samiye Yabanoglu-Ciftci. "Role of serotonin in the regulation of renal proximal tubular epithelial cells." Renal failure 38.7 (2016): 1141-1150.Read more>>
  • Giani et al. Renal tubular angiotensin converting enzyme is responsible for nitro-L-arginine methyl ester (L-NAME)-induced salt sensitivity. (2017) Kidney.Int. 91:856-867Read more>>
  • Thibodeau JF et al. PBI-4050 via GPR40 activation improves adenine-induced kidney injury in mice. Clin Sci (Lond). 2019 Jul 22;133(14):1587-1602. Read more>>
  • Fang-Hao Cai. et al. Diagnostic roles of urinary kidney microvesicles in diabetic nephropathy. Ann Transl Med. 2020 Nov; 8(21): 1431Read more>>
VALIDATION IMAGES