Target Protein: ATG16L
Immunogen Range: 501-607/607
Entrez Gene: 55054
Swiss Prot: Q676U5
Source: KLH conjugated synthetic peptide derived from human ATG16A
Purification: Purified by Protein A.
Storage Buffer: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide.
Storage Condition: Store at -20°C for 12 months..
Background: Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane.
Cross Reactive Species:
For research use only. Not intended for diagnostic or therapeutic use.