bs-41073P

DATASHEET

Entrez Gene: 16176

Swiss Prot: P10749

Source: Recombinant mouse IL-1b protein, C-His protein is expressed in E.coli with C-His. It contains the amino acid sequence of 117-269/269.

Storage Buffer: 0.01M TBS(pH7.4)

Storage: The product should be stored at -70°C or -20°C.

Background:

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. [provided by RefSeq, Jul 2008].

Sequence: 117-269/269

Size: 100ug, 500ug, 20ug

Applications: ELISA(1:500-1000)

Mol. Wt.: 17

Species: Others

For research use only. Not intended for diagnostic or therapeutic use.