bs-4112R-Biotin [Conjugated Primary Antibody]
GABA A Receptor gamma 2 Antibody, Biotin Conjugated
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: GABA A Receptor gamma 2

Immunogen Range: 41-140/475


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 2566

Swiss Prot: P18507

Source: KLH conjugated synthetic peptide derived from human GABRG2/GABA A Receptor gamma 2

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand-gated chloride channel.

Conjugation: Biotin

Excitation/ Emission: N/A

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
IHC-P(1:200-400)
IHC-F(1:100-500)

Predicted Molecular Weight: 51


Cross Reactive Species: Human
Mouse
Rat
Rabbit

Predicted Cross Reactive Species: Dog
Cow
Pig
Horse

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Deng CX et al. Pinellia Total Alkaloids Modulate the GABAergic System in Hippocampal Formation on Pilocarpine-Induced Epileptic Rats. Chin J Integr Med. 2019 May 15.Read more>>
  • Jie-Dan Mu. et al. Acupuncture alleviates spinal hyperreflexia and motor dysfunction in post-ischemic stroke rats with spastic hypertonia via KCC2-mediated spinal GABAA activation. Exp Neurol. 2022 Mar;:114027Read more>>
  • Sun Tian-Yi. et al. Acupuncture improves the structure of spastic muscle and decreases spasticity by enhancing GABA, KCC2, and GABAA_2 in the brainstem in rats after ischemic stroke. NEUROREPORT. 2022 Jun;33(9):399-407Read more>>
  • Li Mingxing. et al. Caspase-1 affects chronic restraint stress-induced depression-like behaviors by modifying GABAergic dysfunction in the hippocampus. TRANSL PSYCHIAT. 2023 Jun;13(1):1-11Read more>>
VALIDATION IMAGES