bs-41231P

DATASHEET

Entrez Gene: 12525

Swiss Prot: P01731

Source: Recombinant mouse CD8 Protein, N-His protein is expressed in E.coli with N-His. It contains the amino acid sequence of 28-196/247.

Storage Buffer: 2M Urea.

Storage: The product should be stored at -70°C or -20°C.

Background:

CD8 (cluster of differentiation 8) is a transmembrane glycoprotein that serves as a co-receptor for the T cell receptor (TCR). Like the TCR, CD8 binds to a major histocompatibility complex (MHC) molecule, but is specific for the class I MHC protein. There are two isoforms of the protein, alpha and beta, each encoded by a different gene. The CD8 co-receptor is predominantly expressed on the surface of cytotoxic T cells, but can also be found on natural killer cells, cortical thymocytes, and dendritic cells.The CD8 molecule is a marker for cytotoxic T cell population. It is expressed in T cell lymphoblastic lymphoma and hypo-pigmented mycosis fungoides.

Sequence: 28-196/247

Size: 50µg, 500µg

Applications: ELISA

Mol. Wt.: 18

Species: Others

For research use only. Not intended for diagnostic or therapeutic use.