bs-41245P

DATASHEET

Entrez Gene: 9518

Swiss Prot: Q99988

Source: Recombinant human GDF15 protein in E.coli with N-His. It contains the amino acid sequence of 195-308/308

Storage Buffer: 0.01M TBS(pH7.4)

Storage: The product should be stored at -70°C or -20°C.

Background:

Growth differentiation factor 15 (GDF15) is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. It has been implicated in a variety of functions directly related to tumorigenicity including antiproliferative and pro-apoptotic effects. BMP proteins are secreted growth factors that are characterized by seven conserved cysteine residues. In general, they are regulators of cell growth and differentiation in both embryonic and adult tissues. GDF15 is an important downstream mediator of DNA damage signaling and a transcriptional target of p53.

Sequence: 195-308/308

Size: 100µg, 500µg, 20µg

Applications: Others

Mol. Wt.: 12.7

Species: Others

For research use only. Not intended for diagnostic or therapeutic use.