bs-41321P

DATASHEET

Entrez Gene: 3932

Swiss Prot: P06239-3

Source: Recombinant human Lck protein isoform 3 is expressed in E.coli with N-His. It contains the amino acid sequence of 222-539/539

Storage Buffer: 4M urea (pH9.0) with 20mM Tris-HCl.

Storage: The product should be stored at -70°C or -20°C.

Background:

This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described. [provided by RefSeq, Jul 2008].

Sequence: 222-539/539

Size: 100µg, 500µg

Applications: Others

Mol. Wt.: 36.4

Species: Others

For research use only. Not intended for diagnostic or therapeutic use.