bs-4140R-Cy5

DATASHEET

Host: Rabbit

Target Protein: NF1

Immunogen Range: 2701-2839/2839

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 4763

Swiss Prot: P21359

Source: KLH conjugated synthetic peptide derived from human Neurofibromin 1

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. [provided by RefSeq, Jul 2008].

Conjugation: Cy5

Excitation/ Emission: 625,650nm/670nm

Size: 100ul

Concentration: 1ug/ul

Applications: IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 147/319

Cross Reactive Species: Human
Mouse

Predicted Cross Reactive Species: Rat
Dog
Horse
Rabbit

For research use only. Not intended for diagnostic or therapeutic use.