bs-4171R [Primary Antibody]
Angiomotin Polyclonal Antibody
www.biossusa.com
[email protected]
800.501.7654 [DOMESTIC]
+1.781.569.5821 [INTERNATIONAL]
DATASHEET

Host: Rabbit

Target Protein: Angiomotin

Immunogen Range: 545-620/1084


Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 154796

Swiss Prot: Q4VCS5

Source: KLH conjugated synthetic peptide derived from human Angiomotin

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Background:

Plays a central role in tight junction maintenance via the complex formed with ARHGAP17, which acts by regulating the uptake of polarity proteins at tight junctions. Appears to regulate endothelial cell migration and tube formation. May also play a role in the assembly of endothelial cell-cell junctions.

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
ELISA(1:500-1000)
IHC-P(1:200-400)
IHC-F(1:100-500)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 118


Cross Reactive Species: Human

Predicted Cross Reactive Species: Mouse
Rat
Dog
Cow
Pig
Horse

For research use only. Not intended for diagnostic or therapeutic use.

PRODUCT SPECIFIC PUBLICATIONS
  • Shimada, Hiroshi, et al. "Loss of tricellular tight junction protein LSR promotes cell invasion and migration via upregulation of TEAD1/AREG in human endometrial cancer." Scientific Reports 7 (2017): 37049.Read more>>
VALIDATION IMAGES

Formalin-fixed and paraffin embedded human placenta tissue labeled with Anti-Angiomotin Polyclonal Antibody, Unconjugated (bs-4171R) at 1:200 followed by conjugation to the secondary antibody and DAB staining


Formalin-fixed and paraffin embedded human colon tissue labeled with Anti-Angiomotin Polyclonal Antibody, Unconjugated (bs-4171R) at 1:200 followed by conjugation to the secondary antibody and DAB staining