bs-42066P-Biotin

DATASHEET

Entrez Gene: 79728

Swiss Prot: Q86YC2

Source: Recombinant human PALB2 protein is expressed in E.coli with His&Trx&S. It contains the amino acid sequence of 841-1186/1186

Storage Buffer: Lyophilized from 0.22um filtered solution in 20mM PB (pH 7.4). 5% trehalose is added as a protectant before lyophilization.

Storage: The product should be stored at -70°C or -20°C.

Background:

This gene encodes a protein that may function in tumor suppression. This protein binds to and colocalizes with the breast cancer 2 early onset protein (BRCA2) in nuclear foci and likely permits the stable intranuclear localization and accumulation of BRCA2. Essential partner of BRCA2 that promotes the localization and stability of BRCA2. Also enables its recombinational repair and checkpoint functions of BRCA2. May act by promoting stable association of BRCA2 with nuclear structures, allowing BRCA2 to escape the effects of proteosome-mediated degradation.

Sequence: 841-1186/1186

Conjugation: Biotin

Excitation/ Emission: N/A

Size: 100µg, 500µg, 20µg

Applications: Others

Predicted Molecular Weight: 38

Cross Reactive Species: Others

For research use only. Not intended for diagnostic or therapeutic use.