bs-42084P

DATASHEET

Entrez Gene: 1755

Swiss Prot: Q9UGM3

Source: Recombinant human DMBT1 protein is expressed in E.coli with C-His. It contains the amino acid sequence of 1313-1662/2413

Storage Buffer: 20mM Tris-HCl (pH8.0) with 8M Urea.

Storage: The product should be stored at -70°C or -20°C.

Background:

DMBT 1 may play roles in mucosal defense system, cellular immune defense and epithelial differentiation. May play a role in liver regeneration. May be an important factor in fate decision and differentiation of transit-amplifying ductular(oval) cells within the hepatic lineage. May function as a binding protein in saliva for the regulation of taste sensation. May play a role as an opsonin receptor for SFTPD and SPAR in macrophages tissues throughout the body, including epithelial cells lining the gastrointestinal tract. Required for terminal differentiation of columnar epithelial cells during early embryogenesis. [Subcellular Location] Secreted. Membrane. [Tissue Specificity] Expressed in von Ebner glands (VEG) (at protein level), olfactory epithelium and the lateral nasal gland. Expressed in transit-amplifying ductular (oval) cells. Up-regulated at day 3 after hepatectomy. Expressed in newly formed bile ducts and in structures resembling intestinal epithelium. Belongs to the DMBT1 family.

Sequence: 1313-1662/2413

Size: 100µg, 500µg

Applications: Others

Mol. Wt.: 38.7

Species: Others

For research use only. Not intended for diagnostic or therapeutic use.