bs-42094P

DATASHEET

Entrez Gene: 72512

Swiss Prot: Q3TBT3

Source: Recombinant mouse STING1 protein is expressed in E.coli with N-His. It contains the amino acid sequence of 215-378/378

Storage Buffer: 0.01M TBS(pH7.4)

Storage: The product should be stored at -70°C or -20°C.

Background:

This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]

Sequence: 215-378/378

Size: 100ug, 500ug, 20ug

Applications: Others

Mol. Wt.: 24.4

Species: Others

For research use only. Not intended for diagnostic or therapeutic use.