DATASHEET
Entrez Gene:
6095
Swiss Prot:
P35398
Source:
Recombinant human RORA protein is expressed in E.coli with N-His. It contains the amino acid sequence of 27-319/523
Storage Buffer:
20mM Tris (pH8.0) with 8M Urea.
Storage:
The product should be stored at -70°C or -20°C.
Background:
The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Also, it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2014]
Sequence:
27-319/523