bs-42119P

DATASHEET

Entrez Gene: 16880

Swiss Prot: P42703

Source: Recombinant mouse LIFR protein is expressed in E.coli with N-His. It contains the amino acid sequence of 903-1092/1092

Storage Buffer: 0.01M TBS(pH7.4)

Storage: The product should be stored at -70°C or -20°C.

Background:

This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding the same protein have been found for this gene.

Sequence: 903-1092/1092

Size: 100ug, 500ug

Applications: Others(N/A)

Mol. Wt.: 23.1

Species: Others

For research use only. Not intended for diagnostic or therapeutic use.