bs-42149P

DATASHEET

Entrez Gene: 170484

Swiss Prot: Q91X05

Source: Recombinant mouse NPHS2 protein is expressed in E.coli with N-His. It contains the amino acid sequence of 126-310/385

Storage Buffer: 20mM Tris (pH8.0) with 8M Urea.

Storage: The product should be stored at -70°C or -20°C.

Background:

Podocin is an important member of a group of proteins shown to be associated with the slit diaphragm. Podocin belongs to the band 7 stomatin family of lipid raft-associated proteins. It is a hairpin like integral membrane protein with intracellular N and C termini. Podocin is located at the insertion site of the slit membrane, and is thought to act as a scaffold protein required to maintain or regulate the structural integrity of the slit diaphragm. It plays a role in the regulation of glomerular permeability, acting probably as a linker between the plasma membrane and the cytoskeleton.

Sequence: 126-310/385

Size: 100µg, 500µg

Applications: Others

Mol. Wt.: 23.2

Species: Others

For research use only. Not intended for diagnostic or therapeutic use.