bs-42186P

DATASHEET

Entrez Gene: 53905

Swiss Prot: Q9NRD9

Source: Recombinant human DUOX1 protein is expressed in E.coli with N-His. It contains the amino acid sequence of 1270-1551/1551

Storage Buffer: 20mM Tris-HCl (pH8.0) with 8M Urea and 5mM DTT.

Storage: The product should be stored at -70°C or -20°C.

Background:

Dual oxidase 1 (DUOX1), a homolog of glycoprotein p91Phox, is expressed in airway epithelium and generates reactive oxygen species (ROS). DUOX1 is a multi-pass membrane protein predominantly expressed in thyrocytes and tracheal surface epithelial cells, as well as thyroid, trachea and bronchium. DUOX1 generates hydrogen peroxide, which is crucial for thyroid peroxidase and lactoperoxidase. It is also involved in thyroid hormone synthesis and lactoperoxidase-mediated antimicrobial defense in mucosa. DUOX1, which also plays a role in mucin expression, is widely expressed in fetal tissues.

Sequence: 1270-1551/1551

Size: 100µg, 500µg

Applications: Others

Mol. Wt.: 34.9

Species: Others

For research use only. Not intended for diagnostic or therapeutic use.