bs-42203P-Biotin

DATASHEET

Entrez Gene: 216799

Swiss Prot: Q8R4B8

Source: Recombinant mouse NALP3 protein is expressed in E.coli with N-Trx-His. It contains the amino acid sequence of 1-93/1033

Storage Buffer: Lyophilized from 0.22um filtered solution in 20mM PB (pH 7.4). 5% trehalose is added as a protectant before lyophilization.

Storage: The product should be stored at -70°C or -20°C.

Background:

May function as an inducer of apoptosis. Interacts selectively with ASC and this complex may function as an upstream activator of NF-kappa-B signaling. Inhibits TNF-alpha induced activation and nuclear translocation of RELA/NF-KB p65. Also inhibits transcriptional activity of RELA. Activates caspase-1 in response to a number of triggers including bacterial or viral infection which leads to processing and release of IL1B and IL18. Subcellular Location : Cytoplasm.

Conjugation: Biotin

Excitation/ Emission: N/A

Size: 100ug,500ug,20ug

Applications: Others()

Mol. Wt.: 28.9

Species: Others

For research use only. Not intended for diagnostic or therapeutic use.