bs-42218P

DATASHEET

Entrez Gene: 4023

Swiss Prot: P06858

Source: Recombinant human LPL protein is expressed in E.coli with N-His. It contains the amino acid sequence of 172-385/475

Storage Buffer: 20mM Tris-HCl (pH8.0) with 8M Urea.

Storage: The product should be stored at -70°C or -20°C.

Background:

Lipoprotein lipase (LPL) is the central enzyme in plasma triglyceride hydrolysis and is secreted by macrophages in the subendothelial space. Evidence has been provided that LPL produced by macrophages in the vessel wall exerts proatherogenic effects. The atherogenic effects of LPL have been mainly attributed to its ability to favor lipid accumulation within macrophages present in the atherosclerotic lesion. Recently, it has also been shown that LPL promote the development of atherosclerosis through facilitation of monocyte adhesion to endothelial cells, stimulation of tumor necrosis factor alpha (TNF ) secretion and induction of vascular smooth muscle cell proliferation.

Sequence: 172-385/475

Size: 100µg, 500µg

Applications: Others

Mol. Wt.: 26.2

Species: Others

For research use only. Not intended for diagnostic or therapeutic use.