bs-42227P

DATASHEET

Entrez Gene: 21934

Swiss Prot: O35305

Source: Recombinant mouse RANK protein is expressed in E.coli with N-Trx-His. It contains the amino acid sequence of 478-625/625

Storage Buffer: 0.01M TBS(pH7.4)

Storage: The product should be stored at -70°C or -20°C.

Background:

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Aug 2012]

Size: 100ug,500ug,20ug

Applications: Others()

Mol. Wt.: 33.1

Species: Others

For research use only. Not intended for diagnostic or therapeutic use.